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Neurology 80 , 949951 (2013)

doi: 10.1016/j.jhazmat.2021.127815 22

Recent findings indicate that organelles containing enzymes for the synthesis of O 2 - and H 2 O 2 can produce OH , which may damage DNA, leading to the development of oxidative DNA adducts

Furthermore, galunisertib inhibited stemness-related activities in invasive HCC cells, reducing colony formation, hepatic spheroid formation, and invasive growth ability [180]