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187 For PD treatment, Sun et al reported ZAAM, a NSC membrane-coated and Apt 19S-conjugated penetrable NP, loaded with ASOs that transiently suppressed the RNA-binding protein PTBP1, thereby reducing neuronal apoptosis and promoting the conversion of astrocytes to neurons (Figure 7C)

Rinaldi G, Rossi M, Fendt S

Hauet T, Bauza G, Goujon J, Caritez J, Carretier M, Eugene M, et al

In this review, we focus on the importance of the composition of DR diets involving methionine restriction (MR), discuss mechanisms involved, and provide examples that illustrate the relationship between MR and longevity through the balance of protein-based dietary regimens