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Heart Palpitations or High Blood Pressure Heart palpitations Increased heart rate Elevated blood pressure Signs and Symptoms of B12 Overdose signs and symptoms of B12 overdose may include: Skin rash or acne Headaches Nausea or diarrhea Anxiety or restlessness Heart palpitations High blood pressure Trouble sleeping How Much Vitamin B12 Is Too Much

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Gradual dose titration : Following the prescribed dose escalation schedule is essentialrushing titration significantly increases side effect severity