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Determination of erythrocyte glutathione redox status The erythrocyte GSH redox status was measured using the commercial GSH assay kit (Cat

Although this remains a complex and somewhat controversial area of study, many aged animal tissues exhibit dampened rhythms characterized by reduced amplitude, increased fragmentation, and impaired stability

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These results confirm the fact that in AD, as in certain other diseases the balance between ATP formation and ion pumping may be disordered resulting in a decrease in intercellular energy charge, and an increase in lactate formation and catabolism of adenylates (Ronquist and Waldenstrm, 2003)