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Continuous translocation of bacteria and its products stimulate the immune cells after identification by pathogen-recognition receptors, typically TLRs, causing overwhelming inflammatory response via producing inflammatory cytokines (25)

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Suspected adverse reactions to metformin or B12 therapy should be reported via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk or the Yellow Card app)

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Biodegradation 29 (6), 525541

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Santos, Hlder A

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