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Results: There was no significant difference in demographics between the PNPLA3 types, although those with MM genotype were younger (mean age 50.9 vs 55.4 for II and 53.1 for IM) and were more likely to have Type 2 Diabetes (45% MM, 38% II, 41% IM)

Isolation of intestinal epithelial cells (IECs) and lamina propria mononuclear cells (LPMCs) Murine IECs and LPMCs were obtained from the colon and ileum as previously described 40