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Strict adherence to refrigeration protocols is mandatory

Typical Post-Injection Timeline First 24-48 hours: Mild to moderate pain at the injection site Localized warmth and redness Slight swelling around the knee Temporary stiffness or reduced range of motion Days 2-3: Gradual reduction in swelling Decreased pain and tenderness Return to normal mobility Possible spongy sensation when walking [4] The American Academy of Orthopaedic Surgeons notes that patients should avoid excessive activity, such as jogging or heavy lifting for the first 48 hours after injection [2]

Additionally, professional athletes should verify anti-doping rules before considering use

Kammerer-Ciernioch J., Klinikum am Weissenhof, Weinsberg, Department of Psychiatry and Psychotherapy