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INTRODUCTION Recent epidemiological studies indicate that 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy) 1 , a synthetic derivative of amphetamine with a range of psychotropic actions, is widely abused by mostly young people during rave parties (large social gatherings characterized by dancing and loud music)

For microbial community analysis, the hypervariable V4 region of bacterial 16S rRNA gene was amplified using specific primers: V4F (5-GTGTGYCAGCMGCCGCGGTAA-3) and V4R (5-CCGGACTACNVGGGTWTCTAAT-3)

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For example, PD patients treated with DHA and EPA capsules (800 mg/day DHA and 290 mg/day EPA) for 6 months experienced a 50% reduction in depressive symptoms, compared to only 25% in the placebo group [181]