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Description

Multiple signaling pathways that initiate inflammatory responses as a result of mitochondrial dysfunction have been discovered, particularly cyclic GMP-AMP synthase (cGAS) - Stimulator of Interferon Genes 1 (STING1) and inflammasome signaling pathways (see Figure 4 ) (158)

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Acad Sci 106: 16831684

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[15] [37] [38] In August 2025, the Food and Drug Administration (FDA) expanded the indication for semaglutide (as Wegovy) to include the treatment of noncirrhotic metabolic-associated steatohepatitis (MASH), formerly known as nonalcoholic steatohepatitis (NASH), with moderate to advanced liver fibrosis (consistent with stages F2 to F3 fibrosis) in adults

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