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These findings establish -syn as a key regulator of neuronal ferroptosis and highlight ether-PLs as potential therapeutic targets in synucleinopathies (Mahoney-Sanchez et al., 2022)

A mild deficiency may have no symptoms, but a more severe or prolonged deficiency can exhibit the following: Microcytic anemia Skin conditions Depression Confusion Lowered immunity Certain conditions can increase the risk of developing a deficiency by interfering with the absorption of vitamin B6: Kidney disease Autoimmune intestinal disorders like celiac disease, ulcerative colitis, and Crohns disease Autoimmune inflammatory disorders such as rheumatoid arthritis Alcoholism Toxicity It is quite unlikely to reach a toxic level of vitamin B6 from food sources alone

Various inhaled pollutants, whether organic or inorganic, can exert profound effects on neurological health through shared mechanistic pathways, including oxidative stress, systemic inflammation, and BBB disruption

Even small increases in BAC can decrease motor coordination, make a person feel sick, and cloud judgment