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We demonstrate that astrocytes, which are intimately involved in regulating BBB function via their endfeet, create a local inflammatory milieu that likely participates in destabilizing BBB integrity

More serious complications of a B12 deficiency include heart disease, infertility, coordination problems, neurocognitive disorders, peripheral neuropathy and vision loss

Macrophage plasticity and polarization in tissue repair and remodelling

Diabetes-related prescriptions typically receive higher approval rates than weight management indications, with coverage rates exceeding 70% for diabetic patients versus 25-40% for obesity diagnoses alone