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This review aims to highlight the central role of OS in the pathophysiology of ALS, specifically focusing on the KEAP1-NRF2 system and its alteration in ALS, while discussing the potential applications of NRF2 activators in ALS therapy

nextGEMS is the first step towards a European ecosystem of km-scale climate research and operational Earth system models, to which WarmWorld, EERIE, Destination Earth, and other projects contribute