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Vitale I, Manic G, Coussens LM, Kroemer G, Galluzzi L

More reports mention the Three-Hit Hypothesis, involving dysregulated lipid metabolism, mitochondrial dysfunction with decreased fat degradation, and oxidative stress that happens in cycles in the progression of MASLD cases [231, 232]

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In addition, curcumin down-regulated CD31and CD105 mRNA (two endothelial cell marker from newly formed vessels) and reduced the content of hemoglobin in glioma cells