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In contrast, although FAM134B has been suggested to interact with the mitochondrial inner membrane protein OPA1 and the FAM134B LIR motif plays a role in mitochondria degradation by assembling phagocytic factors around mitochondria [53], cells in models of excessive ER-phagy preferentially protect energy-producing structures [47]

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Data Availability Statement Data sharing not applicable no new data generated, or the article describes entirely theoretical research.

Notably, fat transplantation to Insr P1195L/ +/HFD mice did not increase adiponectin, suggesting that change in adiponectin did not contribute to improved glycemia