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Fsp1 acts in parallel with gpx4 to inhibit ferroptosis in copd

GPX4, integral in inhibiting lipid peroxidation and closely linked with ferroptosis in stroke patients, shows significantly reduced protein expression in both in vivo and in vitro IS models (Zhu et al., 2022)

Am J Surg 248:116391, 2025

When tested in pancreatectomised dogs the first fraction stimulated secretion from the pancreas while the second seemed to lower blood glucose without activating secretion from the pancreas