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DOI Malmlf K, Johansen PB, Haahr PM, Wilken M, Oxlund H (1999)

This results in a substantial buildup of hydrogen peroxide in the cytosol, which works to reversibly oxidize catalytic cysteine residues in phosphatases, ultimately preventing them from dephosphorylating key downstream TCR signaling proteins, including ZAP-70, PTEN, and LAT (75, 76)