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However, these warning signs represent serious underlying cellular dysfunction that can progress to irreversible complications including subacute combined degeneration , cognitive decline , and neural tube defects in developing pregnancies

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Later Spanish prospectors discovered gold deposits in the narrow canyons of the Salt River upstream from the Phoenix Basin, but the remoteness of the area from Spanish presidios along with its proximity to Apache realms rendered the Spanish development efforts extremely haphazard

19 References Seiwerth, S., Sikiric, P., Grabarevi, ., Zorii, I., Hanevaki, M., Ljubanovi, D., ori, V., Konjevoda, P., Petek, M., Ruman, R., Turkovi, B., Perovi, D., Mikus, D., Jandrijevi, S., Medvidovi, M., Tadi, T., Romac, B., Kos, J., Peri, J., & Kolega, Z