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A similar procedure was used to produce the negative control resins: ovalbumin- and mouse IgG Affi-Gel 15 for the HPX receptor isolations, and for the positive control for TfR1, holo-human Tf Affi-Gel 15 (Sigma-Aldrich, St.Louis, MO) and mouse IgG from Thermo Fisher Scientific

Erastin-induced cell death in HT22 cells could be strongly rescued by Fer-1 (Fig

doi: 10.1016/j.immuni.2020.06.024 147

Nonclinical Toxicology 13.1 Carcinogenesis, Mutagenesis, and Impairment of Fertility Carcinogenesis Valproate was administered orally to rats and mice at doses of 80 and 170 mg/kg/day (less than the maximum recommended human dose on a mg/m 2 basis) for two years