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The integration of APA biomarkers with gene expression profiles, clinical covariates, and other traditional prognostic indicators is expected to construct a more precise diagnostic system, thereby promoting a qualitative leap in personalized cancer treatment (Kandhari et al., 2021)

Immunocytochemistry iRPE cells were fixed in 4% paraformaldehyde (PAF, Inland Europe, Conflans sur Lanterne, France) for 20 min

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