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The enhanced affinity for thiolate anion and activation of enzyme-bound glutathione is governed by an arginine residue of human Mu class glutathione S-transferases

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Additionally, in pSS-related experimental animal studies, SCFAs modulate aberrant activation of B cells and dendritic cells by activating the aryl hydrocarbon receptor (AhR) or by suppressing NF-B signaling, thereby alleviating lymphocyte infiltration in exocrine glands (209)