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Diabetes 59 , 13971406 (2010)

Cartilage and Musculoskeletal Biology Research As noted in the mechanism section, published research has begun to examine this compounds interactions with cartilage biology and chondrocyte function

Following the catabolism of glucose in the cytoplasm as part of glycolysis, the generated pyruvate is transported to the mitochondrial matrix, where it feeds into the TCA, undergoing oxidation to reduce NAD + to NADH, which is the main electron donor of the ETC 87