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Each of these molecules exerts distinct effects on cellular function, both locally and distally, through individual molecular targets [12, 13]

Melatonin is found in various tissues other than the pineal gland, involving the pancreas, liver, brain, lens, thyroid, and others (Mahmood 2019)

Dialysis is a prohibited method under M1.1, as blood is taken out from the patient and filtered, before being reintroduced back into the patients circulatory system