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ERK promotes the expression of the oncogenic factor c-Fos, whereas both p38 and JNK are involved in activating the transcription factor c-Jun (67, 68)

Similarly, we have shown that GSNO loaded hydrogels induce localized dermal vasodilation when applied to intact human skin, as well as to healthy and diabetic rat skin 31,32

For example, in Arabidopsis embryonic roots, division of cells in G1 phase is accelerated if they are in the oxidized state and slowed if they are in the reduced state ( FIGURE 1 In the Arabidopsis shoot apical meristem (SAM), enrichment of in stem cells activates the WUSCHEL gene to maintain stem cell activities, whereas H 2 O 2 accumulation in the peripheral zone (PZ) promotes cell differentiation

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