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This trial found that FUS in one hemisphere improved motor features of Parkinsons disease as evidenced by a decrease in Unified Parkinsons Disease Rating Scale (UPDRS) scores, although some adverse events were reported including speech and gait disturbances and weakness on the treated side

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In yeast and plant, we observed almost no NADPH consumption upon oxidative challenge with H 2 O 2 or diamide in the absence of a cytosolic glutathione reductase ( Figure 5 and 6 )

The Nrf2 pathway is a negative regulator of inflammation according to the hierarchical oxidative stress model [8, 9]