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CagriSema's FDA submission remains on track (decision expected late 2026), but these results put more pressure on the higher-dose REDEFINE 11 trial (readout in the first half of 2027)

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For instance, research shows MOTS-c drives glucose into the pentose phosphate pathway (for anabolic needs and antioxidant defense) rather than burning it immediately via glycolysis, while simultaneously increasing fatty-acid oxidation by upregulating carnitine shuttle activity in mitochondria

content and even correct identity are not guaranteed the way a GMP clinical supply would be