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Ercal says NACA is an improvement over another experimental treatment, the antioxidant N-acetylcysteine (NAC), because it passes more easily across cell membranes, allowing the medication to be used in lower doses

Belloni Fortina, A., & Caroppo, F

The elevated expression of Pfkfb3 in astrocytes facilitates the continuous production of fructose-2,6-bisphosphate, an allosteric activator of phosphofructokinase (PFK), which accelerates glycolysis (Blanger et al., 2011)