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527 Conclusions and perspective Primarily recognized for their role in diabetes mellitus treatment, GLP-1RAs have demonstrated significant benefits in cardiovascular health, skeletal muscle-related diseases, obesity management, and neurodegenerative conditions, among others

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It's important to note that long-term use of certain diabetes medications, including GLP-1 receptor agonists like semaglutide, may be associated with an increased risk of vitamin B12 deficiency [1]