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[DOI] [PubMed] [Google Scholar] 2.Dickinson DA, Forman HJ

Tesamorelin has the strongest evidence for reducing visceral abdominal fat in adults with HIV-associated lipodystrophy, while GLP-1/GIP medications such as semaglutide and tirzepatide are generally stronger options for overall weight loss

Because this approach works with your natural rhythms rather than forcing a rapid change, it tends to produce steady, sustainable improvement rather than an overnight transformation