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Of the two, methimazole is generally preferred because it has fewer side effects than PTU, which can cause liver toxicity in a few patients

Astilbin pretreatment enhances MSC efficacy in AKI and AKI-CKD mice by inducing polarization of macrophages towards an M2-like phenotype via prostaglandin-endoperoxide synthase 2 (PTGS2)-mediated pathways [306]