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Allosteric control of hemoglobin S fiber formation by oxygen and its relation to the pathophysiology of sickle cell disease

Additionally, the exclusion of patients with severe erosive OLP or systemic conditions, while necessary for protocol adherence, restricts the generalizability of the results to these specific subgroups

Saseen reports serving as a member of the monitoring board for two large cardiovascular outcome trials (VESALIUS, OCEAN(a)) sponsored by Amgen

In GST of both subgroups and in mitochondrial GST, these amino acid residues essential for GSH activation are located in the so-called catalytic loop that is next to the first -sheet in the thioredoxin-like domain