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ICE1 can activate the transcription of CBF genes under cold stress, and CBF subsequently can induce the gene expression of CORs by directly binding their promoters, which contribute to plant freezing tolerance ( CBF expression and plant freezing tolerance ( 2 O 2 also can act as an important signaling molecule, which modulates the abiotic stresses tolerance by various pathways ( 2 O 2 can induce MPK3 and MPK6 via the activation of ANP1 ( MPK3 was significantly higher in OE plants compared to WT in both conditions