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A peer-reviewed overview in the International Journal of Molecular Sciences (Araj et al., Medical University of Warsaw, 2025) establishing Epithalon as a highly bioactive pineal tetrapeptide with documented mechanisms spanning telomere maintenance, epigenetic regulation, antioxidant defense, immune recalibration, and circadian rhythm restoration provides the scientific framework for all five mechanisms described in this section

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While cold therapy primarily addresses the acute inflammatory response through physical effects on blood vessels and nerve signaling, BPC-157 works at the cellular and molecular level to promote actual tissue regeneration