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A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib

It is used to treat various types of pain, swelling, stiffness, and joint pain in conditions like rheumatoid arthritis, osteoarthritis, and acute musculoskeletal injuries

[DOI] [PMC free article] [PubMed] [Google Scholar] 103.Gupta I., Hussein O., Sastry K.S., Bougarn S., Gopinath N., Chin-Smith E., Sinha Y., Korashy H.M., Maccalli C

Protease Resistance via D-Amino Acid Architecture The DRI modification fundamentally alters the peptide's metabolic fate compared to conventional L-amino acid peptides