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10.1016/0092-8674(79)90293-9 103 LiuD

FLS: Flavonol synthase

On the other hand, melatonin can regulate the immune system [43,44] and oxidative stress [19,30,38,45,46,47,48], thereby repressing many malignancies [49]

The low constant of dissociation for the NADPH suggests that the reaction can be a very efficient controller, acting as a feedback, which would regulate the enzymatic activity