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Foxp3 stability in iTregs can be greatly increased by optimizing culture conditions, especially by adding epigenetic modifiers such vitamin C (39, 40)

B.LiY.RosselotC.ZhangT.SiddiqM.RajbhandariP.et al (2023)

Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal

It sometimes described by members of the integrative medicine community as potentially having a variety of health benefits, including potentially reducing the size and number of kidney stones