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5.1 TCM monomer 5.1.1 Flavonoids Quercetin, a naturally occurring flavonoid, demonstrates a range of pharmacological properties, such as antioxidant, anti-inflammatory, antidiabetic, and anticancer activities ( Baicalin, a flavonoid derived from the roots of Scutellaria baicalensis , possesses a broad spectrum of pharmacological effects, including anti-inflammatory, antitumor, antibacterial, lipid-lowering, and antioxidant activities ( Atractylodin, the principal bioactive compound in Atractylodes macrocephala , possesses a range of pharmacological properties, including anti-inflammatory, antitumor, cardioprotective, and antioxidant activities ( Plumbagin, a natural naphthoquinone derived from Plumbago zeylanica roots, exhibits multiple pharmacological effects such as antioxidant, antidiabetic, antifungal, and anticancer activities ( 6 A methylation pathway that regulates SLC7A5 translation ( 5.1.2 Alkaloids Berberine, an isoquinoline alkaloid present in numerous Chinese medicinal plants, exhibits diverse pharmacological effects including antibacterial, antidiabetic, and anticancer activities ( Nuciferine, an alkaloid derived from lotus leaves, is used clinically to manage hyperlipidemia and as an adjunct for weight control, owing to its lipid-regulating, insulin-secreting, vasodilatory, antihypertensive, antitumor, and immunomodulatory properties ( Leonuri Herb, a plant of the Lamiaceae family, is medicinally derived from its dried aerial parts