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Among organic nanoparticles, polymers have been extensively used along with AuNPs to make hybrid nanocomposites for various biomedical applications [297, 298]

doi: 10.1016/j.cell.2018.05.003 74 Del PradoL.Jaraz-RodrguezM.AgroM.Zamora-DortaM.AzpiazuN.CallejaM.et al

The REDEFINE 1 trial found that when evaluating the treatment effect regardless of whether patients stayed on treatment, those treated with CagriSema achieved weight loss of 20.4% (from an average baseline body weight of 236 lb) at 68 weeks versus 3.0% (from an average baseline body weight of 235 lb) for the placebo group which was statistically significant

Given their correlation, we conclude that EVs regulate cellular metabolic activity by transferring substances and signaling molecules and facilitating metabolic reprogramming between cells