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An emerging concept is the digital twin for aging, a computational model of a patient that can predict how they would respond to various interventions ( Table 1 summarizes recent single-cell multi-omics findings across cardiovascular and aging contexts and links key cell states to potential clinical uses

Wittstock U, Kliebenstein DJ, Lambrix V, Reichelt M, Gershenson J

Another study including depressed subjects indicated no significant differences in frequency of the T allele or TT genotype between the depressed and healthy controls 77

(2009) cMyc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism, Nature , 458 , 762-765, doi: Altman, B