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Therapeutic Action Powerful anti-inflammatory agent, result of the synergy of action of its components, indicated in acute inflammatory processes of different origin, traumatic or rheumatic, involving musculoskeletal or osteoneuromuscular (lumbago, lumbociatalgias, arthritis, or osteoarthritis)

doi:10.1186/s41205-020-00069-2 90

Given that there is no placebo-controlled human data, no established dose, and a mechanism whose foundational papers were retracted, an absence of noticeable effect is fully consistent with the current evidence it does not necessarily indicate a defective product, the wrong route, or an insufficient duration

The review documented DSIP's widespread distribution throughout the brain and peripheral tissues, its remarkably stable presence in cerebrospinal fluid, and its unusually long-lasting biological effects despite a short plasma half-life of only minutes