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If kidney issues are known or suspected, prioritize a clinician-led review of all supplements and medications to ensure a safe, coordinated plan

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Nevertheless, several of these aspects have been successfully sorted out over recent years through the new technologies available in peptides design field: new bioinformatics tools in combination with other approaches such as virtual screening, structure-based drug design, high throughput screening (HTS) and chemical strategies, provide a comprehensive pharmacological description of putative peptides, improving their chemical and physical features (119, 121, 148)

Multi-center, randomized, placebo-controlled trials of epitalon, BPC-157, TB-500, and Semax in elderly populations could definitively establish efficacy and safety, potentially bringing these agents into mainstream gerontological practice (Wang et al., 2022)