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Under oxidative stress, Nrf2 dissociates from kelch-like ECH-associated protein-1 (Keap1), translocates to the nucleus, and the activated Nrf2 induces the expression of various endogenous antioxidant enzymes [10]

nonetheless, it is linked to gastrointestinal adverse effects, notably nausea and diarrhea, which may restrict its application in some individuals (Papp et al

12 Conclusion This comprehensive review delves into the diverse array of symptoms and their management in patients with cirrhosis, underscoring the profound impact these symptoms have on quality of life