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Description

Astaxanthin enhances autophagy, amyloid beta clearance and exerts anti-inflammatory effects in in vitro models of Alzheimers disease-related blood brain barrier dysfunction and inflammation

For this purpose, activation of adaptive stress responses was investigated for DNA damage (p21), oxidative stress (SRXN1), inflammation (ICAMI), and ER stress (CHOP) using a HepG2-based GFP-reporter assay (Wink et al., 2014, 2017)