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An update on strategies for optimizing polymer-lipid hybrid nanoparticle-mediated drug delivery: exploiting transformability and bioactivity of PLN and harnessing intracellular lipid transport mechanism

Hackam DJ, Upperman JS, Grishin A, Ford HR

Here is a skim over of the current research on T4: Animal and in vitro research In animal models of stroke, traumatic brain injury, and multiple sclerosis, T4 has demonstrated neuroprotective and regenerative properties like supporting axonal growth, remyelination, and angiogenesis, and upregulating expression of tight junction proteins that contribute to blood-brain barrier integrity