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Apremilast, an oral phosphodiesterase 4 (PDE4) inhibitor, in patients with moderate to severe plaque psoriasis: results of a phase III, randomized, controlled trial (Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis [ESTEEM] 1)

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For example, concurrent use with corticosteroids may amplify the potential for fluid retention or electrolyte imbalance, particularly sodium and water retention

Relapse prevention planning can help people prepare for social events, boredom, conflict, and old drinking habits