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Intestinal immune cells, such as macrophages and T cells, undergo significant changes in metabolic pathways during inflammatory states, which not only affect their functional status but also determine the nature and intensity of the immune response

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It has been shown that alveolar epithelial lining fluid of patients with ARDS is deficient in total GSH compared to normal subjects (107), and neutrophil-mediated oxidants release leads to GSH deficiency and lung cell injury (107)

Mechanisms of PLGA-based nanoparticles transport across the BBB The transport of PLGA-based nanoparticles across the BBB is mediated by active or passive transporters 118