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Disclosure of interest: All authors: nothing to disclose Poster session I - DIAGNOSIS / ETIOLOGY 04.00 - DIAGNOSIS / ETIOLOGY - 04.01 - DIAGNOSIS/INVESTIGATION OF STROKE ETIOLOGY P327 - ESOC25-999 MICROEMBOLIC SIGNAL DETECTION: A 5-YEAR EXPERIENCE AT A GERMAN NEUROVASKULAR CENTER Lili Laura Bruta 1 , Irena Kovacic 1 , David Pollinger 2 , David Olmes 2 , Ralf Linker 2 , Felix Schlachetzki 1 1 Center for Vascular Neurology and Intensive Care Medicine (Center II) at the Department of Neurology at the University of Regensburg, Regensburg, Germany, 2 Department of Neurology at the University of Regensburg, Regensburg, Germany Background and Aims: Microembolic signal detection (MES-D) is a potent sonographic biomarker for increased stroke risk but still has no widespread impact on stroke therapy