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1o), supporting MeCbl specifically inhibits GSDME-mediated pyroptosis but not apoptosis

doi: 10.1021/acs.est.5b05387 233 ZhouXKramerJPCalafatAMYeX

3.6 Molecular docking and SPR analysis Given that the differentially expressed genes were primarily enriched in the AGE/RAGE signaling pathway, RAGE was hypothesized to be a potential target mediating AB4s therapeutic pharmacological effects in sepsis