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Alkylene used alone or as part of alkylene glycol for example, refers to a divalent saturated, straight-chained or branched alkyl group as defined herein

6.3 Metabolic diseases Aging imposes progressive physiological changes that compromise metabolic homeostasis and increase susceptibility to the development of conditions such as insulin resistance, visceral obesity, and type 2 diabetes (T2D) (Poggiogalle et al., 2018)