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[2] Injectable dexamethasone appears on the World Health Organization Model List of Essential Medicines and is considered a standard of care for cerebral edema, acute asthma exacerbations, spinal cord compression, and adrenal crisis

Additionally, the gastrointestinal (GI) absorption efficiencies and bloodbrain barrier (BBB) penetration capabilities were evaluated using the BOILED-Egg classification model, which categorizes the compounds according to their predicted passive absorption and central nervous system access based on the apparent polarity (TPSA) and lipophilicity (WLOGP) values ( Results ChE inhibitory effects of the phenolic compounds As shown in Table 1, all compounds from various chemical groups were tested against 10 mM of the ChEs, of which 12 compounds were able to inhibit AChE, while 8 compounds achieved BChE inhibition over 50%

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Abstract Tamoxifen is the accepted therapy for patients with estrogen receptor- (ER)-positive breast cancer