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Glutathione - Synthesis SFRBM Education Program Dickinson et al.5 + NADP NADPH Glutathione Reductase GSSG GSH Glutathione H O H O Peroxidase 2 2 2 LOH LOOH PSSP PSSG PSH Glutathione - redox cycling Glutathione - Synthesis SFRBM Education Program Dickinson et al.6 Glutathione uses and losses The glutathione S-transferases (GST) serve a protective role by adding GSH to a molecule, targeting it for export from the cell

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(4) The extracellular matrix imparts structural integrity to the tissues and contains a higher collagen content which provides rigidity and serves as a barrier for the transportation of nanoparticles

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